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I receive my
B.Sc. degree from the University of Alberta, in Honors Pharmacology.
During this time, I completed two research projects in the Gati lab
related to nucleoside transporters and leukemia. I also worked for
Isotechnika, Inc. for a summer in the drug discovery department and
for a year after convocation on projects related to drug metabolism.
I am currently a PhD candidate in the Hitt lab. My project is related
to targeting adenoviruses to breast cancer. Adenoviruses normally
bind to the receptors CAR and αV-Integrin on the surface of cells.
This project involves genetically modifying the viruses to bind to
receptors in the EGFR family, since these receptors are often
overexpressed in breast cancer, and testing the binding and uptake of
retargeted adenoviruses.
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Selected Poster Presentations
1. S.
MacLeod, M Elgadi, G Bossi, K Agopsowicz, F Graham, and
MM Hitt, Targeting Adenoviral Vectors to HER3/4 Expressing
Breast Cancer Cells. 2008 ACRI Meeting, Banff, AB, CAN.
Nov 25-27, 2008.
2. S. MacLeod, M Elgadi, G Bossi, K Agopsowicz, F
Graham, and MM Hitt, Adenovirus Vectors Targeted to
HER3/4 Receptors for Breast Cancer Gene Therapy. 2007
American Society of Gene Therapy, Seattle, USA. May30 -
June3, 2007.
3. S.
MacLeod, K. Agopsowicz, M. Elgadi, F. Graham, and M.M.
Hitt, HER3/4 Adenovirus Targeting: Cell Surface
Expression and Knockdown of Receptors. 2006 ACB Annual
Research Meeting, Banff, AB, CAN. Nov 7-9, 2006.
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