Yan, L., Mieulet, V., Burgess, D., Findlay, G.M., Sully, K. , Procter, J. , Goris, J., Janssens, V., Morrice, N.A. and Lamb, R.F (2009). PP2AT61ε is an inhibitor of MAP4K3 in nutrient signaling to mTOR. Molecular Cell, in press.
Yan L., Mieulet, V and Lamb, R.F. (2008). Preview: mTORC2 is the hydrophobic motif kinase for SGK1. Biochem J 416, 19-21.
Mieulet, V. and Lamb, R.F. (2008). Preview. Shooting the messenger: CULLIN’ insulin signalling with Fbw8. Dev. Cell Jun;14(6):816-7.
Findlay GM, Yan L, Procter J, Mieulet V, Lamb R. F. (2007). A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling. Biochem J. 403, 13-20.
Yan L, Findlay GM, Jones R, Procter J, Cao Y, Lamb R.F. (2006). Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase. J. Biol Chem. 281, 19793-7.
Findlay, G.M., L.S. Harrington, and R.F. Lamb. (2005). TSC1-2 tumour suppressor and regulation of mTOR signaling: linking cell growth and proliferation? Current Opinion in Genetics and Development 15, 69-76.
Harrington L.S., Findlay G.M., and Lamb R.F. (2005) Restraining PI3K: mTOR signaling goes back to the membrane. Trends in Biochemical Science 30, 35-42.
Harrington, L. S., Findlay, G.M., Gray, A., Tolkacheva, T., Wigfield, S., Rebholz, H., Barnett, J., Leslie, N.R., Cheng, S., Shepherd, P.R., Gout, I., Downes, C.P. and Lamb, R.F. (2004) The TSC1-2 tumor suppressor controls insulin-PI3K signaling via IRS proteins. Journal of Cell Biology 166, 213. |