Michael Weinfeld

Principal Investigator

DNA Repair Therapeutics

Research Overview

Leader in DNA damage and repair field, specializing in Polynucleotide Kinase/Phosphatase (PNKP) enzyme research and therapeutic development for cancer treatment.

DNA Repair EnzymesCancer TherapeuticsEnvironmental Carcinogenesis

Research Focus

DNA Repair Enzymes

Investigation of key DNA repair enzymes, particularly PNKP, and their roles in maintaining genome stability and their potential as therapeutic targets.

Cancer Therapeutics

Development of novel therapeutic strategies that target DNA repair pathways in cancer cells, including combination approaches and personalized medicine.

Environmental Carcinogenesis

Study of how environmental factors cause DNA damage and contribute to cancer development, with focus on repair pathway responses.

Biomarker Development

Identification and validation of biomarkers related to DNA repair capacity for cancer prognosis and treatment selection.